Functional cell phenotyping, microdomain discovery and spatial systems pathology

Access paper: https://doi.org/10.1101/2020.10.02.322529 This paper shows how to build a data-driven and computationally unbiased phenotypic hierarchy of cell types, cell states, and their spatial configurations from multi to hyperplexed tissue samples to characterize spatial intratumor heterogeneity,  discover recurrence-associated microdomains, and harness spatial network biology for precision medicine applications. This work in combination with our Nature […]